Name: Jaypee Essentials of Pharmacology For Dentistry 4th Edition
Brand: Amit Book Depot
Price: 1150 INR
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Jaypee Essentials of Pharmacology For Dentistry 4th Edition

by Madhurima

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23 Customer Review

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Q1

Which drug is the first choice for anaphylaxis management in a dental office?

A1

Epinephrine (adrenaline) intramuscularly (0.3–0.5 mg, 1:1000) is first-line. Antihistamines and corticosteroids are adjuncts.
Q2

Why are tetracyclines avoided in children under 8 years for dental infections?

A2

Tetracyclines cause permanent yellow-brown tooth discoloration and enamel hypoplasia due to chelation with calcium in developing teeth.
Q3

Which local anaesthetic is preferred in patients with cardiac arrhythmias?

A3

Prilocaine or mepivacaine without epinephrine is preferred; lidocaine with epinephrine is relatively safe but avoid in uncontrolled arrhythmias.
Q4

What is the mechanism of action of metronidazole against anaerobic dental pathogens?

A4

Metronidazole is reduced by bacterial nitroreductases, forming toxic compounds that damage DNA, effective against anaerobes like Porphyromonas gingivalis.
Q5

Which NSAID is most effective for acute post-endodontic pain?

A5

Ibuprofen (400–600 mg) or diclofenac (50 mg) provides superior analgesia; ketorolac is an option for severe pain short-term.
Q6

Why should aspirin not be used for dental pain in a child with viral fever?

A6

Aspirin increases risk of Reye’s syndrome—acute encephalopathy and liver failure—in children with chickenpox or influenza.
Q7

Which vasoconstrictor in local anaesthetic can precipitate a hypertensive crisis?

A7

Levonordefrin and high-dose epinephrine (>0.04 mg) can raise blood pressure; avoid in uncontrolled hypertension or on nonselective beta-blockers.
Q8

Which antifungal is preferred for treating oral candidiasis (thrush) in denture wearers?

A8

Miconazole oral gel or nystatin suspension (100,000 U/mL) four times daily for 7–14 days. Fluconazole for refractory cases.
Q9

What is the mechanism of action of fluoride in preventing dental caries?

A9

Fluoride promotes remineralization of enamel, inhibits bacterial enolase (reducing acid production), and disrupts plaque biofilm metabolism.
Q10

Why is clindamycin associated with pseudomembranous colitis in dental patients?

A10

Clindamycin suppresses normal gut flora, allowing Clostridioides difficile overgrowth, producing toxin-mediated colonic inflammation and diarrhea.

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Have Doubts Regarding This Product ? Ask Your Question

Q1

Which drug is the first choice for anaphylaxis management in a dental office?

A1

Epinephrine (adrenaline) intramuscularly (0.3–0.5 mg, 1:1000) is first-line. Antihistamines and corticosteroids are adjuncts.
Q2

Why are tetracyclines avoided in children under 8 years for dental infections?

A2

Tetracyclines cause permanent yellow-brown tooth discoloration and enamel hypoplasia due to chelation with calcium in developing teeth.
Q3

Which local anaesthetic is preferred in patients with cardiac arrhythmias?

A3

Prilocaine or mepivacaine without epinephrine is preferred; lidocaine with epinephrine is relatively safe but avoid in uncontrolled arrhythmias.
Q4

What is the mechanism of action of metronidazole against anaerobic dental pathogens?

A4

Metronidazole is reduced by bacterial nitroreductases, forming toxic compounds that damage DNA, effective against anaerobes like Porphyromonas gingivalis.
Q5

Which NSAID is most effective for acute post-endodontic pain?

A5

Ibuprofen (400–600 mg) or diclofenac (50 mg) provides superior analgesia; ketorolac is an option for severe pain short-term.
Q6

Why should aspirin not be used for dental pain in a child with viral fever?

A6

Aspirin increases risk of Reye’s syndrome—acute encephalopathy and liver failure—in children with chickenpox or influenza.
Q7

Which vasoconstrictor in local anaesthetic can precipitate a hypertensive crisis?

A7

Levonordefrin and high-dose epinephrine (>0.04 mg) can raise blood pressure; avoid in uncontrolled hypertension or on nonselective beta-blockers.
Q8

Which antifungal is preferred for treating oral candidiasis (thrush) in denture wearers?

A8

Miconazole oral gel or nystatin suspension (100,000 U/mL) four times daily for 7–14 days. Fluconazole for refractory cases.
Q9

What is the mechanism of action of fluoride in preventing dental caries?

A9

Fluoride promotes remineralization of enamel, inhibits bacterial enolase (reducing acid production), and disrupts plaque biofilm metabolism.
Q10

Why is clindamycin associated with pseudomembranous colitis in dental patients?

A10

Clindamycin suppresses normal gut flora, allowing Clostridioides difficile overgrowth, producing toxin-mediated colonic inflammation and diarrhea.

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